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Episodes

Date Title & Description Contributors
2020-07-20

  ESMO-Magnitude of Clinical Benefit Scale (V1.1) for early breast cancer therapies

We evaluated the applicability of the scale and assessed the reasonableness of the generated scores in early breast cancer. Form 1 of the ESMO-MCBS v1.1 provided a generally robust tool for scoring of adjuvant breast cancer studies. Six shortcomings we... 		  BMJ talk medicine author
2020-06-28

  ESMO-Magnitude of Clinical Benefit Scale of adjuvant colon cancer trials and meta-analyses

Form 1 of the European Society for Medical Oncology-Magnitude of Clinical Benefit Scale (ESMO-MCBS) serves to grade therapies with curative intent. Form 1 provided very reasonable grading and expert field testers confirmed the reasonableness of generat... 		  BMJ talk medicine author
2020-06-04

  Adjuvant and neoadjuvant therapies in melanoma

The therapeutic landscape in melanoma is evolving rapidly. In this podcast, Jonathan Lim (a member of the ESMO Young Oncologists Committee) interviews Dr Teresa Amaral (the current chair of the ESMO Young Oncologists Committee and an expert in melanoma... 		  BMJ talk medicine author
2020-04-05

  Emerging targets in cancer immunotherapy

The advent of cancer immunotherapy has radically changed the field of oncology by improving the way many malignancies, including several aggressive and orphan diseases, are being treated with subsequent major improvement of patients’ prognosis. The fir... 		  BMJ talk medicine author
2020-04-05

  News in breast cancer 2019

Anna Berghof talks to Matteo Lambertini - Department of Medical Oncology, U.O.C. Clinica di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, Genova, Italy. The year 2019 has brought relevant new biological and clinical evidence to further impr... 		  BMJ talk medicine author
2020-03-25

  Cancer care during the spread of Covid-19 in Italy: a young oncologist's perspective

The Covid-19 pandemic is currently active all over Europe and especially in Italy. In this podcast Anna Berghoof discusses with Matteo Lambertini - Department of Medical Oncology, U.O.C. Clinica di Oncologia Medica, IRCCS Ospedale Policlinico San Marti... 		  BMJ talk medicine author
2020-02-12

  ESMO Presidential Symposium: ClarIDHy - ivosidenib in patients with advanced cholangiocarcinoma

Advanced cholangiocarcinoma is associated with a particular impaired survival prognosis. So far targeted therapies with relevant clinical efficacy are missing. isocitrate dehydrogenase 1 (IDH1) mutations are observed in a fraction of patients with chol... 		  BMJ talk medicine author
2020-01-29

  News on the horizon in glioblastoma therapy

Glioblastoma is the most frequent primary malignant brain tumor in adults. Methylation of the O-6-methylguanine-DNA methyltransferase (MGMT) promotor is of prognostic as well as of predictive value, as patients with MGMT promotor methylation survive lo... 		  BMJ talk medicine author
2019-12-20

  Highlights in Lung Cancer 2019

There has been a lot of exciting trials in lung cancer reported in 2019. In this podcast, Jonathan Lim (YOC member) speaks to Professor Sanjay Popat about how these studies are practice-changing in the context of the current treatment landscape, and hi... 		  BMJ talk medicine author
2019-10-03

  Current biomarkers in immunotherapy

Immunotherapy approaches have revolutionized medical oncology in the last years. However, still only a fraction of patients is responding. Given the risk of side effects without efficacy, therefore, biomarkers providing reliable and reproducible predic... 		  BMJ talk medicine author