Mufti Hussain Kamani was born to a Hindu revert-to-Islam and Muslim father in Elizabethtown, Kentucky. With the blessings and du’a (supplications) of his parents, Mufti Hussain Kamani underwent a journey of a lifetime in pursuit of sacred Islamic knowledge. He began his pursuit of the Islamic sciences at the young age of six to memorize the entire Quran at the acclaimed Darul Uloom Madania in Buffalo, New York. By the blessings of Allah, subhanahu wa ta’ala, he was able to complete this momentous task in 1999. Having the growing thirst to quench more knowledge, Mufti Kamani then traveled across the world to the United Kingdom to attain more advanced formal Islamic authorizations in the field of Islamic theology. He studied at Darul Uloom Bury, the renowned seminary of the great revivalist and scholar of Hadith, Shaykh-ul-Hadith Zakariyya Kandhlawi (Rahmatullahi Alayh). Mufti Kamani completed the traditional six-year curriculum covering the Arabic language, Arabic morphology, Islamic jurisprudence, Tafseer (exegis) of the Holy Qur’an, Hadith (Prophetic Sciences), philosophy, and Aqeedah (Islamic Creed) under the guidance of some of the pioneer scholars in England, including Shaykh Yusuf Motala, Shaykh Hashim, Shaykh Bilal and Shaykh Abdur Raheem bin Dawood amongst others. Upon graduation he was then was specially selected to enter a post-graduate level course in Islamic Law and Legal Verdicts (Fatwa). He completed this course in two years and received formal authorization in it as well.

Alongside his religious studies, Mufti Kamani was blessed with having the opportunity to study the secular and academic sciences. He completed his graduate degree in Business Management from the University of Coventry in England as well.