In this interview, Dr. Jennie Johnstone tells us about a strain of gram-negative bacteria called carbapenemase-producing Enterobacteriaceae (CPE) that is resistant to most antibiotics. She also discusses what the public and the health care system can do to help prevent the spread of drug-resistant organisms. Dr. Johnstone is infection prevention and control physician-scientist at Public Health Ontario and infectious disease specialist for St. Joseph’s Health Centre in Toronto. She co-authored a practice article in the CMAJ titled "Five things to know about...Emerging multidrug-resistant bacteria." Full practice article (subscription required): www.cmaj.ca/lookup/doi/10.1503/cmaj.170110 ----------------------------------- Subscribe to CMAJ Podcasts on iTunes, Stitcher, Overcast, Instacast, or your favourite aggregator. You can also follow us directly on our SoundCloud page. Our podcasts are also released on www.cmaj.ca and on www.cmajblogs.com.