Here we discuss the science behind the COVID-19 mRNA vaccines, their development, and mechanisms of action. Featuring: Melis Tekant, Chad Stein, Edward Chen and Samantha Tracy Citations: CDC. “COVID-19 and Your Health.” Centers for Disease Control and Prevention, 11 Feb. 2020, https://www.cdc.gov/coronavirus/2019-ncov/vaccines/different-vaccines/mrna.html. Mandavilli, Apoorva. “The Coronavirus Is Mutating. What Does That Mean for Us?” The New York Times, 20 Dec. 2020, https://www.nytimes.com/2020/12/20/health/coronavirus-britain-variant.html. Laing, Aislinn. “Inside J&J’s Latam COVID Vaccine Trial, a Rush to Recruit Is Followed by Disappointment.” Reuters, 21 Dec. 2020, https://www.reuters.com/article/us-health-coronavirus-vaccines-latinamer-idUSKBN28V1DE Pfizer-BioNTech COVID-19 Vaccine EUA Fact Sheet for Recipients and Caregivers | FDA. https://www.fda.gov/media/144414/. Pinkbook | Home | Epidemiology of Vaccine Preventable Diseases | CDC. 6 Nov. 2020, https://www.cdc.gov/vaccines/pubs/pinkbook/index.html. Understanding and Explaining MRNA COVID-19 Vaccines | CDC. 17 Dec. 2020, https://www.cdc.gov/vaccines/covid-19/hcp/mrna-vaccine-basics.html. Yang, Edward, et al. “Decay Rates of Human MRNAs: Correlation With Functional Characteristics and Sequence Attributes.” Genome Research, vol. 13, no. 8, Aug. 2003, pp. 1863–72, doi:10.1101/gr.1272403.