Visual effects wizardry meets machine learning in this conversation about virtual humans with Doug Roble and Matthias Wittman of Digital Domain. From Virtual Tupac, Benjamin Button, to Thanos, Digital Domain has created some of the most iconic virtual characters in media & entertainment. Now, the company is expanding its efforts into the burgeoning field of virtual humans, lifelike 3D avatars combining Hollywood quality photorealism on the front end, with AI and machine learning in the back. We talk about virtual humans as an artistic concept, a business proposition, as well as the talent and attitude required to succeed in this exciting new medium for creativity.