Dr. Sue Yom, Editor-in-Chief, hosts a discussion of radiation-induced senescence with Dr. Marjan Boerma, Radiation Biology Section Editor at the Red Journal and Professor and Director of the Division of Radiation Health at the University of Arkansas for Medical Sciences, and Dr. Agnès François, Research Engineer in the Radiobiology of Medical Exposure Laboratory at the Institute for Radiological Protection and Nuclear Safety in Fontenay-aux-Roses, France, specializing in mouse models investigating the role of macrophages and bronchiolar epithelium in acute and late injury after focal lung irradiation. They discuss a paper recently published in the Red Journal, "Deciphering the Dynamic Molecular Program of Radiation-Induced Endothelial Senescence."