Overview: Duration of therapy is an important target of antimicrobial stewardship interventions that can be challenging to implement successfully. This podcast will briefly review the updated literature which seems to be coming more frequent recently and describe best practices when implementing shorter durations of therapy safely within the context of an antimicrobial stewardship program. Speakers: Dimitri Drekonja, MD, MS Marisa Holubar, MD, MS Rebekah Wrenn, PharmD, BCIDP (moderator)