The Patient Safety Incident Response Framework (PSIRF) sets out the NHS’s approach to developing and maintaining effective systems and processes for responding to patient safety incidents for the purpose of learning and improving patient safety. In the north west, a collaboration involving NHS England, Aqua, Health Innovation Manchester and the Innovation Agency are delivering the programme. This podcast was recorded at St Helens Rugby Stadium on 6th December 2022 at the second of four learning sessions arranged by the North West Collaborative. Featuring interviews with speakers and delegates, the podcast offers a snapshot of how the framework is being shared and received across the region.