Dr Kerry Costello and Dr Deepak Kumar discuss a BSJM paper that investigated gait and physical activity predictors of cartilage worsening in people with knee osteoarthritis from the MOST study, using a machine learning model. Kerry and Deepak do a brilliant job of explaining the biomechanical variables, and the advantages of machine learning, and what these findings might mean for clinicians treating people with knee osteoarthritis. Link to paper: https://bjsm.bmj.com/content/early/2023/03/02/bjsports-2022-106142 Connect with Kerry: https://mae.ufl.edu/people/faculty/primary/profiles/kerry-costello/