Medical Industry Feature   /     The Endothelin System and IgAN: Emerging Evidence

Subtitle
Duration
00:00:00
Publishing date
2025-01-28 00:00
Link
https://reachmd.com/programs/medical-industry-feature/the-endothelin-system-and-igan-emerging-evidence/29181/
Contributors
Enclosures
https://reachmd.com/programs/medical-industry-feature/the-endothelin-system-and-igan-emerging-evidence/29181/podcast/55842.mp3?partner=itunes
audio/mpeg

Shownotes

Guest: Donald Kohan, MD, PhD

Increased formation of renal endothelin one is associated with renal injury.1 In several studies, activation of the ETA receptor has been shown to contribute to IgA nephropathy (IgAN) progression, and markers of endothelin system activity are elevated in patients with the disease.2,3-5 Join Dr Donald Kohan as he dives into the latest research on this connection, which could provide insight into new tailored therapy approaches for IgAN patients. Dr Kohan is a nephrologist at University of Utah Health in Salt Lake City.

References:

  1. Kohan DE, Barton M. Kidney Int. 2014;86(5):896-904. doi:10.1038/ki.2014.143
  2. Kohan DE et al. Kid Int Rep. 2023;8(11):2198-2210. doi:10.1016/j.ekir.2023.07.023
  3. Lehrke I et al. J Am Soc Nephrol. 2001;12:2321-2329. doi.org/10.1681/ASN.v12112321
  4. Zanatta CM et al. Ren Fail. 2012;34(3):308-315. doi:10.3109/0886022X.2011.647301
  5. Tycova I et al. Physiol Res. 2018;67:93-105. doi.org/10.33549/physiolres.933670

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