In this conversation, Professor Alex Tups discusses his extensive research on metabolic regulation, focusing on the roles of leptin and insulin in the brain. He shares insights into the discovery of butane, a compound found in the Dahlia flower, and its potential to improve blood sugar regulation and combat neuroinflammation. The discussion highlights the importance of diet, gut health, and the synergistic effects of flavonoids in promoting overall well-being. Professor Tups emphasizes the need for further research and clinical trials to validate the benefits of his findings. In this conversation, Alexander Tups and Lisa Tamati discuss the journey of research from the lab to market, focusing on the supplement Dahlia 4 and its potential impact on health, particularly in relation to metabolic dysregulation and neuroinflammation. They explore the importance of consumer awareness regarding supplements, the role of circadian rhythms in health, and the need for proactive health measures. The discussion emphasizes the unique mechanism of Dahlia 4 in targeting brain inflammation and its implications for conditions like Alzheimer's disease. Takeaways: Leptin and insulin play crucial roles in metabolic regulation. Neuroinflammation is a key factor in insulin resistance. Dahlia4 is a supplement derived from the Dahlia flower. Flavonoids can have synergistic effects on health. Diet and gut health significantly impact overall well-being. Research shows potential for reversing pre-diabetes. Oral hygiene is linked to brain health. Clinical trials are ongoing for Dahlia 4's effectiveness. The brain is a master organ in regulating metabolism. Natural compounds can have varying effects on health. The importance of feedback from users to improve health products. Research must translate into real-world applications for maximum impact. Basic research is crucial for developing new drugs and supplements. Supplements can be brought to market faster than traditional drugs. Consumer awareness is key in choosing effective supplements. Metabolic dysregulation is a growing concern for aging populations. Neuroinflammation may be addressed with targeted supplements. Regular eating patterns can support circadian rhythms and metabolic health. Dahlia4 targets brain inflammation, offering a unique approach. Proactive health measures can mitigate risks of chronic diseases. If you would like to try DAHLIA4 you can now find it in our range at www.lisatamati.com Dahlia4 BIO Alexander Tups pursued his academic journey in Biology, initially studying at the Heinrich Heine University of Duesseldorf and the Philipps University of Marburg. He earned a Diploma in Biology at the latter institution, focusing on Animal Physiology, Genetics, and Developmental Biology. He further advanced his education through a Marie Curie and Boehringer Ingelheim Fonds Scholarship, undertaking a Ph.D. at the Rowett Research Institute, one of the UK's leading nutrition research centres and the Philipps University of Marburg. In 2005 he graduated with "summa cum laude (highest distinction) " for his research on the neuroendocrine mechanism that regulates seasonal body weight. Following his Ph.D., Alexander Tups served as a postdoctoral fellow at the University of Otago from 2006-2008. In recognition of his potential, he received a prestigious junior group leader grant in nutrition research from the German Ministry of Education and Research in 2007, amounting to €1,500,000. This grant allowed him to establish an independent research group called 'neuronal nutrition physiology' at the Philipps University of Marburg, where he explored the impact of nutrient sensing in the brain on the regulation of body weight and glucose homeostasis as one of the youngest independent group leaders in Germany. From 2012-2014 in addition to his group leader role he was Head of Department for Animal Physiology at this institution before he was appointed at the University of Otago in 2014 in Physiology. Throughout his career, Alex Tups has contributed significantly to his field, publishing 48 peer reviewed research papers, the vast majority as lead author. His research has contributed to our understanding of how the brain controls body weight and blood sugar levels. His work has been internationally recognized with notable awards, such as the Michael Harbuz Price in neuroendocrine research in the UK in 2009, the Ernst and Berta Sharrer Award in Germany in 2014, the Commercialisation Researcher Award at Otago University in 2023 and the Research Excellence Price by the Physiological Society of New Zealand in 2023. Alexander reviews research for leading international journals and grant agencies including for Harvard University, the British Welcome Trust and the French and German National Research Agencies. He has advised the city council of his home town, Dunedin, on the impact of artificial lighting on human Health supported by his research which contributed to the installation of modern warm street lighting in Dunedin. His research has been funded by Return on Science, Otago Innovation, the Royal Society of Marsden Fund, the Health Research Council, the German Ministry of Research and the German Research Foundation. Personalised Health Optimisation Consulting with Lisa Tamati Lisa offers solution focused coaching sessions to help you find the right answers to your challenges. Topics Lisa can help with: Lisa is a Genetics Practitioner, Health Optimisation Coach, High Performance and Mindset Coach. She is a qualified Ph360 Epigenetics coach and a clinician with The DNA Company and has done years of research into brain rehabilitation, neurodegenerative diseases and biohacking. She has extensive knowledge on such therapies as hyperbaric oxygen, intravenous vitamin C, sports performance, functional genomics, Thyroid, Hormones, Cancer and much more. She can assist with all functional medicine testing. Testing Options Comprehensive Thyroid testing DUTCH Hormone testing Adrenal Testing Organic Acid Testing Microbiome Testing Cell Blueprint Testing Epigenetics Testing DNA testing Basic Blood Test analysis Heavy Metals Nutristat Omega 3 to 6 status and more Lisa and her functional medicine colleagues in the practice can help you navigate the confusing world of health and medicine . She can also advise on the latest research and where to get help if mainstream medicine hasn't got the answers you are searching for whatever the challenge you are facing from cancer to gut issues, from depression and anxiety, weight loss issues, from head injuries to burn out to hormone optimisation to the latest in longevity science. Book your consultation with Lisa Join our Patron program and support the show Pushing the Limits' has been free to air for over 8 years. Providing leading edge information to anyone who needs it. But we need help on our mission. Please join our patron community and get exclusive member benefits (more to roll out later this year) and support this educational platform for the price of a coffee or two You can join by going to Lisa's Patron Community Or if you just want to support Lisa with a "coffee" go to https://www.buymeacoffee.com/LisaT to donate $3 Lisa’s Anti-Aging and Longevity Supplements Lisa has spent years curating a very specialized range of exclusive longevity, health optimizing supplements from leading scientists, researchers and companies all around the world. This is an unprecedented collection. The stuff Lisa wanted for her family but couldn't get in NZ that’s what it’s in her range. Lisa is constantly researching and interviewing the top scientists and researchers in the world to get you the best cutting edge supplements to optimize your life. Subscribe to our popular Youtube channel with over 600 videos, millions of views, a number of full length documentaries, and much more. You don't want to miss out on all the great content on our Lisa's youtube channel. Youtube Order Lisa's Books Lisa has published 5 books: Running Hot, Running to Extremes, Relentless, What your oncologist isn't telling you and her latest "Thriving on the Edge" Check them all out at https://shop.lisatamati.com/collections/books Perfect Amino Supplement by Dr David Minkoff Introducing PerfectAmino PerfectAmino is an amino acid supplement that is 99% utilized by the body to make protein. PerfectAmino is 3-6x the protein of other sources with almost no calories. 100% vegan and non-GMO. The coated PerfectAmino tablets are a slightly different shape and have a natural, non-GMO, certified organic vegan coating on them so they will glide down your throat easily. Fully absorbed within 20-30 minutes! No other form of protein comes close to PerfectAminos Listen to the episode with Dr Minkoff here: Use code "tamati" at checkout to get a 10% discount on any of their devices. Red Light Therapy: Lisa is a huge fan of Red Light Therapy and runs a Hyperbaric and Red Light Therapy clinic. If you are wanting to get the best products try Flexbeam: A wearable Red Light Device https://recharge.health/product/flexbeam-aff/?ref=A9svb6YLz79r38 Or Try Vielights’ advanced Photobiomodulation Devices Vielight brain photobiomodulation devices combine electrical engineering and neuroscience. To find out more about photobiomodulation, current studies underway and already completed and for the devices mentioned in this video go to www.vielight.com and use code “tamati” to get 10% off Enjoyed This Podcast? If you did, subscribe and share it with your friends! If you enjoyed tuning in, then leave us a review and share this with your family and friends. Have any questions? You can contact my team through email (support@lisatamati.com) or find me on Facebook, Twitter, Instagram and YouTube. For more episode updates, visit my website. You may also tune in on Apple Podcasts. To pushing the limits, Lisa and team
In this conversation, Professor Alex Tups discusses his extensive research on metabolic regulation, focusing on the roles of leptin and insulin in the brain. He shares insights into the discovery of butane, a compound found in the Dahlia flower, and its potential to improve blood sugar regulation and combat neuroinflammation. The discussion highlights the importance of diet, gut health, and the synergistic effects of flavonoids in promoting overall well-being. Professor Tups emphasizes the need for further research and clinical trials to validate the benefits of his findings. In this conversation, Alexander Tups and Lisa Tamati discuss the journey of research from the lab to market, focusing on the supplement Dahlia 4 and its potential impact on health, particularly in relation to metabolic dysregulation and neuroinflammation. They explore the importance of consumer awareness regarding supplements, the role of circadian rhythms in health, and the need for proactive health measures. The discussion emphasizes the unique mechanism of Dahlia 4 in targeting brain inflammation and its implications for conditions like Alzheimer's disease.
Takeaways:
If you would like to try DAHLIA4 you can now find it in our range at www.lisatamati.com Dahlia4
BIO
Alexander Tups pursued his academic journey in Biology, initially studying at the Heinrich Heine University of Duesseldorf and the Philipps University of Marburg. He earned a Diploma in Biology at the latter institution, focusing on Animal Physiology, Genetics, and Developmental Biology. He further advanced his education through a Marie Curie and Boehringer Ingelheim Fonds Scholarship, undertaking a Ph.D. at the Rowett Research Institute, one of the UK's leading nutrition research centres and the Philipps University of Marburg. In 2005 he graduated with "summa cum laude (highest distinction) " for his research on the neuroendocrine mechanism that regulates seasonal body weight. Following his Ph.D., Alexander Tups served as a postdoctoral fellow at the University of Otago from 2006-2008. In recognition of his potential, he received a prestigious junior group leader grant in nutrition research from the German Ministry of Education and Research in 2007, amounting to €1,500,000. This grant allowed him to establish an independent research group called 'neuronal nutrition physiology' at the Philipps University of Marburg, where he explored the impact of nutrient sensing in the brain on the regulation of body weight and glucose homeostasis as one of the youngest independent group leaders in Germany. From 2012-2014 in addition to his group leader role he was Head of Department for Animal Physiology at this institution before he was appointed at the University of Otago in 2014 in Physiology. Throughout his career, Alex Tups has contributed significantly to his field, publishing 48 peer reviewed research papers, the vast majority as lead author. His research has contributed to our understanding of how the brain controls body weight and blood sugar levels. His work has been internationally recognized with notable awards, such as the Michael Harbuz Price in neuroendocrine research in the UK in 2009, the Ernst and Berta Sharrer Award in Germany in 2014, the Commercialisation Researcher Award at Otago University in 2023 and the Research Excellence Price by the Physiological Society of New Zealand in 2023. Alexander reviews research for leading international journals and grant agencies including for Harvard University, the British Welcome Trust and the French and German National Research Agencies. He has advised the city council of his home town, Dunedin, on the impact of artificial lighting on human Health supported by his research which contributed to the installation of modern warm street lighting in Dunedin. His research has been funded by Return on Science, Otago Innovation, the Royal Society of Marsden Fund, the Health Research Council, the German Ministry of Research and the German Research Foundation.Personalised Health Optimisation Consulting with Lisa Tamati
Lisa offers solution focused coaching sessions to help you find the right answers to your challenges.
Topics Lisa can help with:
Lisa is a Genetics Practitioner, Health Optimisation Coach, High Performance and Mindset Coach.
She is a qualified Ph360 Epigenetics coach and a clinician with The DNA Company and has done years of research into brain rehabilitation, neurodegenerative diseases and biohacking.
She has extensive knowledge on such therapies as hyperbaric oxygen, intravenous vitamin C, sports performance, functional genomics, Thyroid, Hormones, Cancer and much more. She can assist with all functional medicine testing.
Testing Options
Comprehensive Thyroid testing
DUTCH Hormone testing
Adrenal Testing
Organic Acid Testing
Microbiome Testing
Cell Blueprint Testing
Epigenetics Testing
DNA testing
Basic Blood Test analysis
Heavy Metals
Nutristat
Omega 3 to 6 status
and more
Lisa and her functional medicine colleagues in the practice can help you navigate the confusing world of health and medicine .
She can also advise on the latest research and where to get help if mainstream medicine hasn't got the answers you are searching for whatever the challenge you are facing from cancer to gut issues, from depression and anxiety, weight loss issues, from head injuries to burn out to hormone optimisation to the latest in longevity science. Book your consultation with Lisa
Join our Patron program and support the show
Pushing the Limits' has been free to air for over 8 years. Providing leading edge information to anyone who needs it. But we need help on our mission.
Please join our patron community and get exclusive member benefits (more to roll out later this year) and support this educational platform for the price of a coffee or two
You can join by going to Lisa's Patron Community
Or if you just want to support Lisa with a "coffee" go to
https://www.buymeacoffee.com/LisaT to donate $3
Lisa’s Anti-Aging and Longevity Supplements
Lisa has spent years curating a very specialized range of exclusive longevity, health optimizing supplements from leading scientists, researchers and companies all around the world.
This is an unprecedented collection. The stuff Lisa wanted for her family but couldn't get in NZ that’s what it’s in her range. Lisa is constantly researching and interviewing the top scientists and researchers in the world to get you the best cutting edge supplements to optimize your life.
Subscribe to our popular Youtube channel
with over 600 videos, millions of views, a number of full length documentaries, and much more. You don't want to miss out on all the great content on our Lisa's youtube channel.
Order Lisa's Books
Lisa has published 5 books: Running Hot, Running to Extremes, Relentless, What your oncologist isn't telling you and her latest "Thriving on the Edge"
Check them all out at
https://shop.lisatamati.com/collections/books
Perfect Amino Supplement by Dr David Minkoff
Introducing PerfectAmino
PerfectAmino is an amino acid supplement that is 99% utilized by the body to make protein.
PerfectAmino is 3-6x the protein of other sources with almost no calories.
100% vegan and non-GMO.
The coated PerfectAmino tablets are a slightly different shape and have a natural, non-GMO, certified organic vegan coating on them so they will glide down your throat easily.
Fully absorbed within 20-30 minutes!
No other form of protein comes close to PerfectAminos
Listen to the episode with Dr Minkoff here:
Use code "tamati" at checkout to get a 10% discount on any of their devices.
Red Light Therapy:
Lisa is a huge fan of Red Light Therapy and runs a Hyperbaric and Red Light Therapy clinic. If you are wanting to get the best products try
Flexbeam: A wearable Red Light Device
https://recharge.health/product/flexbeam-aff/?ref=A9svb6YLz79r38
Or Try Vielights’ advanced Photobiomodulation Devices
Vielight brain photobiomodulation devices combine electrical engineering and neuroscience.
To find out more about photobiomodulation, current studies underway and already completed and for the devices mentioned in this video go to
www.vielight.com and use code “tamati” to get 10% off
Enjoyed This Podcast?
If you did, subscribe and share it with your friends!
If you enjoyed tuning in, then leave us a review and share this with your family and friends.
Have any questions? You can contact my team through email (support@lisatamati.com) or find me on Facebook, Twitter, Instagram and YouTube.
For more episode updates, visit my website. You may also tune in on Apple Podcasts.
To pushing the limits,
Lisa and team